IT- bra is disposable patch can be worn by women over a period of 2 to 12 hours to screen for breast tissue abnormalities. Data from these thermal sensors is picked up by a Bluetooth (or USB) enabled device which is then uploaded via the Internet into a predictive analytics center for analysis and transferred back directly to the patient or physician.

Cyrcadia breast patches, fitted with sensors, track temperature changes in variance over time believed to be a circadian cellular change caused by a reduced PER1 and PER2 protein expression in the presence of breast cancer. When tissue is healthy, the Cyrcadia predictive algorithmic output displays an irregular variant metabolic pattern.